Improved Automated Radiosynthesis of [11C]PBR28
نویسندگان
چکیده
منابع مشابه
Improved Automated Radiosynthesis of [11C]PBR28
Microglial activation is commonly identified by elevated levels of the 18 kDa translocator protein (TSPO) in response to several inflammatory processes. [(11)C]PBR28 is one of the most promising PET tracers to image TSPO in both human and non-human primates. In this study, we optimized the radiolabeling procedure of [(11)C]PBR28 for higher radiochemical yield, radiochemical purity, and specific...
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ژورنال
عنوان ژورنال: Scientia Pharmaceutica
سال: 2015
ISSN: 0036-8709,2218-0532
DOI: 10.3797/scipharm.1505-06